FACTORS ASSOCIATED WITH PRECANCEROUS CERVICAL LESIONS IN WOMEN CARRIED OUT BY AN EARLY DETECTION WITH VISUAL ACETIC ACID INSPECTION METHOD IN PADANG PASIR PUBLIC HEALTH CENTER IN PADANG CITY
DOI:
https://doi.org/10.31674/mjmr.2019.v03i02.005Abstract
Cervical cancer is a malignant tumor that grows inside the cervix. The most common cause of cervical cancer is infection with Human PapillomaVirus (HPV).Risk factor is thought to be related with cervical cancer are reproductive age, smoking, low socio economic, duration oral contraceptive and early first intercourse.Visual inspection with acetic acid (VIA) is an attractive screening method for early-phase cervical cancer. About 366 women was examined using this method at Puskesmas Padang Pasir and among these women 137 (37.4%) with test-positive. The purpose of this study is to determine what factors are associated with cervical pre-cancer lesions in women who perform early detection using visual inspection method of acetic acid (IVA) at Puskesmas Padang Pasir Padang.This study method is the analytical cross-sectional design. The study population was women who perform early detection using visual inspection with acetic acid (VIA) method and 80 women were selected to be recruited from 699 respondents who came in 2015 until 2017 with simple random sampling technique. This study was hold from May 15th until June 2nd, 2017. Data were analyzed univariate using frequency distributions and bivariate using Chi Square.Results showed that the risk factor that have a statistically significant relationship to the incidence of cervical precancerous lesions (p<0.05) was duration of oral contraceptive use (OR=5.802, CI95%: 2.117 – 15.901). Factors that showed no statistically significant relationship (p>0.05) to the incidence of cervical precancerous lesions were age with p=0.365 and early first intercourse with p=0.433. The conclusions are there is no significant relationship between age and early first intercourse with cervical precancerous lesions and there is significant relationship between duration of oral contraceptive use with cervical precancerous lesions. It is expected that Puskesmas Padang Pasir can improve the early detection of cervical cancer by society.
Keywords:
Early First Intercourse, Duration of Oral Contraceptive Use, Cervical Precancerous LesionsDownloads
References
Anindita, W. & Martini, S. (2006). Risk Factors for Vaginal Candidiasis Events in KB Acceptor. The Indonesian Journal of Public Health, 3(1), pp 24-28.
Aziz, M.F., Andrijono, & dan Saifuddin, A.B.(2006). Onkologi dan Ginekologi Buku Acuan Nasional. Yayasan Bina Pustaka Sarwono Prawirohardjo. Jakarta
Cibula, D., Gompel, A., Mueck, A.O., Vecchia, C, Hannaford, P.C., Skouby, S.O.,Zikan, M. & Desuk, L. (2010). Hormonal contraception and risk of cancer. Human Reproduction Update, 16(6), pp 631-650.
Edianto, D., Taufik, E. & Aziz, M.F. (2001). The histopathological predictor factors in the recurrence of cervical carcinoma stage IB - IIA after radical hysterectomy. Predictor Factors in the Recurrence of Cervical Cancer, 10(2), pp 79-83
Li, C., Wu, M., Wang, J., Zhang, S., Zhu, L., Pan, J. & Zhang, W. (2010). Population-based Study on the Risks Cervical Lesion and Human Papillomavir Infection among Women in Beijing, People Republic of China. Cancer Epidemiology, Biomarkers and Prevention, 19(10), pp 2655-2664
Louie, K.S., Sanjose, S.D., Diaz, M., Castellsague, X., Herrero, R., Meijer, C.J., Shah, K., Franceschi, S., Munoz, N. & Bosch, F.X. (2009). Early age at first sexual intercourse and early pregnancy are risk factors for cervical cancer in developing countries. British Journal of Cancer,100(7), pp 1191-1197
Lynge, E., Lönnberg S. & Törnberg, S. (2017). Cervical cancer incidence in elderly women- biology or screening history? European Journal of Cancer, 74, pp 82-88.
Manuaba, F., Kusuma, G.Y.S., Putra, G.M., Megadhana, W. & Sanjaya, N.H. (2017). Characteristic of patients with pelvic organ prolapse in obstetric and Gynaecologic outpatient clinic in Sanglah Hospital, Bali, Indonesia from January 2014 to December 2015. Bali Medical Journal, 6(1), pp 76-81
Ministry of Health of the Republic of Indonesia. (2015). Indonesia Health Profile. Retrieved from:http://www.depkes.go.id/resources/download/pusdatin/profil-kesehatan- indonesia/indonesian%20health%20profile%202015.pdf
Moreno, V., Bosch, F.X., Muñoz, N., Meijer, C.J.,Shah, K.V.,Walboomers, J.M., Herrero, R. & Franceschi, S. (2002). Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case case control. The lancet, 359(9312), pp 1085-1092.
Nugroho. H., Askandar, B. & Handayani, L. (2015). Incidence and capability to treat cervical cancer In Dr. Soetomo General Hospital Surabaya Indonesia. Asian Society of Gynecologic Oncology. Retrieved from: https://ejgo.org/src/4th-Biennial-Meeting- 2015.pdf
Nurwijaya, Hartanti, Andrijono & dan H.K. Suheimi. 2010. Cegah dan Deteksi Dini Kanker Serviks. Surabaya: Elex Media Komputindo.
Padang City Health Office. (2015). Health Profiles of Padang CITY. Padang, Indonesia: Padang City Government
Pradya, N. (2015). Age Relationship and Use of Long-Term Contraceptive Pills for Positive IVA Results as Early Detection of Cervical Cancer Events. Majority, 4(7), pp 13-18
Shi, N, Lu, Q., Zhang, J., Li, L., Zhang, X., Dong, Y., Zhang F., Gao, W. (2017). Analysis of risk factors for persistent infection of asymptomatic women with high-risk human papilloma virus. Human Vaccines & Immunotherapeutics, 13(6), pp 1-7.
Smith, J.S., Green, J., Gonzalez, A. B.D., Appleby, P., Peto, J., Plummer, M., Franceschi, S. & Beral, V. (2003). Cervical cancer and use of hormonal contraceptives: a systematic review. The Lancet, 361(9364), pp 1159-1167.
Stanford Children’s Health. (2019). Contraception/Birth Control. Retrieved from: https://www.stanfordchildrens.org/en/topic/default?id=contraceptionbirth-control-85- P01509
Susanti I, Boon ME, Tasche, M.J.& Kok, L.P. (1989). Human papillomavirus (HPV)- associated male and female genital carcinomas in a Hindu population. Cancer 64, pp559-65
Wiyono, S., Iskandar, T.M., Suprijono &Visual Acetate (IVA). (2008). Inspection for Early Detection of Cervical Precancerous Lesions. Media Medika Indonesiana, 43(3), pp 116-121
Zikan, M. & Desuk, L. (2010). Hormonal contraception and risk of cancer. Human Reproduction Update,16(6), pp 631-650.
