RELATIONSHIP BETWEEN WOMEN'S BODY MASS INDEX AND SUCCESS RATE OF IN VITRO FERTILIZATION

Authors

  • Noura Mohamed Eltoukhi Clinical instructor at Maternal & Newborn health nursing, Faculty of Nursing, Cairo University.
  • Hanan Fahmy Azzam Assistant Professor of Maternal & Newborn health nursing, Faculty of Nursing, Cairo University
  • Mohamed Hani Professor of Obstetrics & Gynecology, Faculty of Medicine, Cairo University
  • Amel Shaaban Abdel-Monem Lecturer of Maternal & Newborn health nursing, Faculty of Nursing, Cairo University.

Abstract

Background: Infertility considered a traumatic event, and assisted reproductive technology is now a revolution for treatment. In vitro fertilization is a commonly performed procedure. Many factors affect the procedure success, including body mass index.

Aim: This study aimed to explore the relationship between body mass index &in Vitro fertilization success.

Subject & methods: Descriptive co relational design prospectively investigated 100 women who underwent in vitro fertilization with age from 25 - 35 years, selected upon the basis of the defined criteria. Women were classified into groups according to body mass index, i.e., (underweight n=5), (normal-weight n=9), (overweight n=36), (obese I n=32), (obese II n=14), and (obese III n=4). Then, body mass index, related variations in cycle parameters and clinical pregnancy rates of women were investigated.

Results: Current research shows that 81% of women had primary infertility. Doses of drugs for ovulation induction, ovulation induction cycles, and chemical pregnancy rate were found to be negatively affected by body mass index. Higher implantation rates were associated with normal body weight. Clinical pregnancy rates were lower in the obesity grade III than in other groups.

Conclusion: Current study evaluated the relationship between body mass index and in vitro fertilization success portraying that clinical pregnancy rates are significantly lower with obesity grade III than in the other groups.

Keywords:

Body mass index, Success rate, In vitro fertilization

Downloads

Download data is not yet available.

References

Abdel-Khalek,A.M.(1989).Thedevelopmentand validation of an Arabic form of the STAI: Egyptian results. Personality and Individual Differences,10(3), pp 277-285.

Agarwal, A., Mulgund, A., Hamada, A. & Chyatte, M. R. A. (2015). Aunique view on male infertility around the globe. Reproductive Biologyand Endocrinology, 13(37), pages 9.

Alassiri, S., Almadany, H., Ateeq, K., & Tamim, H. (2016). Effect of Female Body Mass Index on the Outcome of IVF / ICSI Treatment Cycles in Saudi Women. Clinical Studies in Obesity,3(2), pp 527–536.

Ali, H. A. E., Ebraheem, O. M., & Mohamed, S. N. (2013). FactorsAffectingPregnancyRatesofinVitroFertilization. Journal of American Science,9(3), pp 484-495.

Bailey, A. P., Hawkins, L. K., Missmer, S. A., Correia, K. F., & Yanushpolsky, E. H. (2014). Effect of body mass index on in vitro fertilization outcomes in women with poly cystic ovary syndrome. American Journal of Obstetrics and Gynecology,211(2), pp 83–90.

Centers for Disease Control and Prevention (2016). Reproductive Health: Infertily FAQs. Available at: https://www.cdc.gov/reproductivehealth/infertility/

El-attar, A. (2008). Body Weight Effect on the Outcome of Assisted Reproductive Treatment. Suez Canal University Medical Journal,11(1), pp 131 – 136

Gibreel, A., Eladawi, N., El-Gilany, A. H., Allakkany, N., & Shams, M. (2015). How do Egyptian gynecologists manage infertility? Cross-sectional study. Journal of Obstetrics and Gynaecology Research, 41(7),pp 1067–1073.

Hill, M. J., Hong, S., & Frattarelli, J. L. (2011). Body mass index impacts in vitrofertilization stimulation. ISRN Obstetrics and Gynecology,2011, 929251. Huxley, R., Mendis, S., Zheleznyakov, E., Reddy, S., & Chan, J. (2010). Body mass index, waist circumference and waist: hip ratio as predictors of cardiovascular risk—a review of the literature. European Journal of Clinical Nutrition, 64(1), pp 16-22.

Julian, L. J. (2011). Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care and Research,63 (SUPPL. 11), pp 467–472.

Kasim, K., & Roshdy, A. (2014). Body Mass Index and Pregnancy Outcome after Assisted Reproduction Treatment. International Journal of Reproductive Medicine,2014, pp 257974

Legge, A., Bouzayen, R., Hamilton, L., & Young, D. (2014). The impact of maternal body mass index on in vitro fertilization outcomes.JournalofObstetricsand Gynaecology Canada,36(7), pp 613–619.

Louis, J. F., Thoma, M. E., Sørensen, D. N., McLain, A. C., King, R. B., Sundaram, R., Keiding, N. and Buck Louis, G. M. (2013). The prevalence of couple infertility in the United States from a male perspective: evidence from a nationally representative sample. Andrology,1(5), pp 741-8.

Luke, B., Brown, M. B., Stern, J. E., Missmer, S. a., Fujimoto, V. Y., & Leach, R. (2011). Female obesity adversely affects assisted reproductive technology (ART) pregnancy and live birthrates. Human Reproduction, 26(1), pp 245–252.

Mansour ,R., El-Faissal, Y., & Kamal, O. (2014). The Egyptian IVF registry report: Assisted reproductive technology in Egypt 2005. Middle East Fertility Society Journal,19(1), pp 16–21.

Martin, J. A., Hamilton, B. E., Osterman, M. J., Curtin, S. C., & Matthews, T. J. (2015). Births: Final data for 2013. National Vital Statistics Reports: From the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System, 64(1), pp 1–65. Matalliotakis, I., Cakmak, H., Sakkas, D., Mahutte, N., Koumantakis, G., & Arici, A. (2008). Impact of body mass index on IVF and ICSI outcome: a retrospective study. Reproductive biomedicine online,16(6), pp 778-783.

Moini, A., Amirchaghmaghi, E., Javidfar, N., Tehraninejad, E. S., Sadeghi, M., Khafri, S., & Shabani, F. (2008). The effect of body mass index on the outcome of IVF/ICSI cycles in non polycystic ovarysyndromewomen. International Journal of Fertility and Sterility,2(2), pp 82–85.

Moragianni, V. A., Jones, S.-M. L., & Ryley, D. A. (2012). The effect of body mass index on the outcomes of rst assisted reproductive technology cycles. Fertility and Sterility,98(1), pp 102–108.

Orvieto, R. (2015). Comment on “the role of overweight and obesity in in vitrofertilization outcomes of poor ovarian responders.” BioMed Research International,2015, pp 5–10.

Petanovski, Z., Dimitrov, G., Ajdin, B., Hadzi-Lega, M., Sotirovska, V., Matevski, V., Stojkovska, S., Saltirovski, S., Suslevski, D. & Petanovska, E. (2011). Impact of body mass index (BMI) and age on the outcome of the IVF process. Prilozi,32(1), pp 155–171.

Robertson, S. (2015). Infertility Prevalence. News: Medical LifeSciences.Availableat:http://www.news-medical.net/health/Infertility-Prevalence.aspx

Sallam, H. (2013) Infertility in Egypt: Science, Myth, and Religion. Available at: http://www.iaac.ca/en/infertility-in-egypt-science-myth-and-religion-3)11-11-2014

Sarais,V.,Pagliardini,L.,Rebonato,G.,Papaleo,E., Candiani, M., & Viganò, P. (2016). A Comprehensive Analysis of Body MassIndex Effecton inVitroFertilization Outcomes, Nutrients, 8(3), pp 109.

Sathya, A., Balasubramanyam, S., Gupta, S., & Verma, T. (2010). Effect of body mass index on in vitrofertilization outcomes in women. Journal of Human Reproductive Sciences,3(3), pp 135–138.

Sharma, R., (2013). Impact of BMI on IVF outcome in females - AProspective study. International Journal of cScienti and Research Publications,3(2), pp 1–8.

Spielberger, C. D., Gorsuch, R. L., Lushene, R., Vagg, P. R., & Jacobs, G. A. (1983). Manual for the State-Trait AnxietyInventory.

Palo Alto,CA: Consulting Psychologists Press. Sunderam, S., Kissin, D. M., Crawford, S., Anderson, J. E., Folger, S. G., Jamieson, D. J., eld,Bar W. D.; Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC (2015). Assisted reproductive technology surveillance - United States, 2012. MMWR Surveill Summ,62(9), pp 1–24.

Toma, C., Veleva, Z., Tiitinen, A., Vilska, S., Hyde, C., Martikainen, H., & Tapanainen, J. S. (2008). High and low BMI increase the risk of miscarriage after IVF / ICSI and FET. Human Reproduction,23(4), pp 878–884.

Turner, K., Reynolds-May, M. F., Zitek, E. M., Tisdale, R. L., Carlisle, A. B., & Westphal, L. M. (2013). Stress and Anxiety Scores in First and Repeat IVF Cycles: A Pilot Study. PLoS ONE, 8(5), pp 19–21.

Zegers-Hochschild, F., Adamson, G. D., de Mouzon, J., Ishihara, O., Mansour, R., Nygren, K., Sullivan, E. & Vanderpoel, S. (2009). International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009.

Downloads

Published

03-04-2017

How to Cite

Noura Mohamed Eltoukhi, Hanan Fahmy Azzam, Mohamed Hani, & Amel Shaaban Abdel-Monem. (2017). RELATIONSHIP BETWEEN WOMEN’S BODY MASS INDEX AND SUCCESS RATE OF IN VITRO FERTILIZATION . Malaysian Journal of Medical Research (MJMR), 1(2), 8-17. Retrieved from https://ejournal.lucp.net/index.php/mjmr/article/view/125

Metrics