STUDY OF MICRONUCLI FREQUENCY IN DIFFERENT LEAD EXPOSED POPULATION

Authors

  • Ajanta Halder Department of Genetics, Ma Sarada College of Nursing, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, 99, Sarat Bose Road, Kolkata - 700 026, India
  • Madhusnata De Department of Genetics, Ma Sarada College of Nursing, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, 99, Saraf Bose Road, Kolkata - 700 026, India

Abstract

Lead and lead compounds play a significant role in modern industry; a wide variety of population is at risk of occupational exposure and lead is suspected to be a human carcinogen. Chronic exposure to sub toxic levels of mutagenic metals is a cause of concern as such exposure has been seen to result in genetic modifications. Analysis of micronucleus (MN) in exfoliated buccal cells is a sensitive method for monitoring genetic damage in human population. In our study, we used four different occupational groups, Group l; Directly lead exposed garage workers (30 cases), Group 2; Directly exposed lead smelter factory workers (30 cases), Group 3; Indirectly lead exposed hospital staff (30 cases), Group 4;Control group (30 cases).

We analysed MN frequencies in exfoliated buccal cells and compared the directly and indirectly exposed groups with control groups.

The mean (±SD) MN(%) frequencies in exfoliated buccal cells from group 1 and 2 were 0.12±0.05 and 0.15±0.05 respectively and the mean (±SD) MN(%) frequencies in exfoliated buccal cells from group 3 and 4 were 0.06±0.04 and 0.05±0.04 respectively.

Keywords:

Micronucli Frequency, Mutagenic metals, Buccal cells, Chronic exposure

Downloads

Download data is not yet available.

Downloads

Published

03-01-2011

How to Cite

Ajanta Halder, & Madhusnata De. (2011). STUDY OF MICRONUCLI FREQUENCY IN DIFFERENT LEAD EXPOSED POPULATION. The Malaysian Journal of Nursing (MJN), 2(3), 29-31. Retrieved from https://ejournal.lucp.net/index.php/mjn/article/view/610

Metrics