Diagnostic Accuracy of Clinical Examination, Ultrasonography, and Radiography for Developmental Dysplasia of the Hip in Infants: A Prospective Diagnostic-Accuracy Cohort Study

Authors

DOI:

https://doi.org/10.31674/mjn.2026.v18i01.014

Abstract

Background: Developmental Dysplasia of the Hip (DDH) requires early recognition and appropriate age imaging to reduce delayed diagnosis and the need for more complex treatment. Nurses contribute to risk recognition, caregiver education, referral coordination, and follow-up, although nursing outcomes were not evaluated in this diagnostic study. Objectives: To compare the diagnostic performance of clinical examination, ultrasonography, and radiography for DDH in at-risk infants using a common composite reference standard. Methods: This prospective diagnostic-accuracy cohort study included 416 infants aged from birth to 12 months who had at least one stated risk factor for DDH. Participants underwent standardized clinical examination, Graf-method ultrasonography, and age-appropriate anteroposterior pelvic radiography. Final DDH classification was based on follow-up radiography at approximately 6 months of age and pediatric orthopedic adjudication. Sensitivity, specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV), with 95% Confidence Intervals (CIs), were reported for each index test. Results: Ultrasonography had a reported sensitivity of 71.0% (95% CI, 65.5%-76.0%) and a specificity of 69.0% (95% CI, 60.7%-76.3%). Clinical examination had a sensitivity of 54.0% (95% CI, 48.2%-59.7%) and specificity of 64.0% (95% CI, 55.5%-71.7%), whereas radiography had a sensitivity of 71.0% (95% CI, 65.5%-76.0%) and specificity of 39.0% (95% CI, 31.1%-47.5%). Conclusion: Ultrasonography provided the most favorable reported balance of sensitivity and specificity in this selected high-risk cohort, while clinical examination remained an important first-line assessment and radiography provided age-dependent structural information. The findings support a coordinated, age-appropriate diagnostic pathway rather than reliance on a single modality. For nursing practice, the results emphasize standardized risk documentation, timely communication with pediatric and radiology teams, caregiver education, and closed-loop follow-up; however, direct nursing competencies, interventions, and outcomes should be evaluated in future studies.

Keywords:

Clinical Examination, Developmental Dysplasia of the Hip, Diagnostic Accuracy, Infant, Nursing Practice, Radiography, Ultrasonography

Downloads

Download data is not yet available.

References

Ahmed, Q. A., & Alanee, A. H. (2023). Evaluation the efficacy of Barlow and Ortolani test in the diagnosis of developmental dysplasia of the hip in infant in Salah Al-deen General Hospital. The Medical Journal of Tikrit University, 29(2), 36–43. https://doi.org/10.25130/mjotu.29.1.6

Akber, M. A., Tiryag, A. M., & Habib, A. I. (2024). Nurses’ knowledge concerning developmental dysplasia of the hip: A cross-sectional study. The Medical Journal of Basrah University, 42(1), 114–120. https://doi.org/10.33762/mjbu.2024.149970.1243

Al-Saeedy, B. A. T., & Redah, S. M. (2022). Use of limited hip abduction as a predictor for developmental dysplasia of the hip. Medical Journal of Babylon, 19(3), 471–475. https://doi.org/10.4103/mjbl.mjbl_85_22

Altman, D. G., & Bland, J. M. (1994). Diagnostic tests 2: Predictive values. BMJ, 309(6947), 102. https://doi.org/10.1136/bmj.309.6947.102

Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., Lijmer, J. G., Moher, D., Rennie, D., de Vet, H. C. W., Kressel, H. Y., Rifai, N., Golub, R. M., Altman, D. G., Hooft, L., Korevaar, D. A., & Cohen, J. F. (2015). STARD 2015: An updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. https://doi.org/10.1136/bmj.h5527

Chavoshi, M., Soltani, G., Shafiei Zargar, S., Wyles, C. C., Maradit Kremers, H., & Rouzrokh, P. (2022). Diagnostic performance of clinical examination versus ultrasonography in the detection of developmental dysplasia of hip: A systematic review and meta-analysis. Archives of Bone and Joint Surgery, 10(5), 403–412. https://doi.org/10.22038/ABJS.2021.60504.2984

Cheok, T., Smith, T., Wills, K., Jennings, M., Rawat, J., & Foster, B. (2023). Universal screening may reduce the incidence of late diagnosis of developmental dysplasia of the hip: A systematic review and meta-analysis. The Bone & Joint Journal, 105-B(2), 198–208. https://doi.org/10.1302/0301-620X.105B2.BJJ-2022-0896.R1

Harper, P., Gangadharan, R., Poku, D., & Aarvold, A. (2021). Cost analysis of screening programmes for developmental dysplasia of the hip: A systematic review. Indian Journal of Orthopaedics, 55, 1402–1409. https://doi.org/10.1007/s43465-021-00501-7

Hassan, W. M., Mohammed, B. I., Shukri, A. A., & Hasan, J. N. (2025). Impact of traditional swaddling practices on the risk and early detection of developmental dysplasia of the hip in Duhok City, Iraq: Prospective observational study. Indian Journal of Orthopaedics, 59(9), 1440–1446. https://doi.org/10.1007/s43465-025-01386-6

Inagaki-Asano, A., Honda, C., Matsumoto, H., & Yoshioka-Maeda, K. (2024). Universal ultrasound screening for developmental dysplasia of the hip among infants in community settings in Japan: A scoping review. SAGE Open Nursing, 10, Article 23779608241272462. https://doi.org/10.1177/23779608241272462

Karnik, A., Lawande, A., Lawande, M. A., Patkar, D., Aroojis, A., & Bhatnagar, N. (2021). Practice essentials of imaging in early diagnosis of DDH. Indian Journal of Orthopaedics, 55(6), 1466–1479. https://doi.org/10.1007/s43465-021-00539-7

Krysta, W., Dudek, P., Pulik, Ł., & Łęgosz, P. (2024). Screening of developmental dysplasia of the hip in Europe: A systematic review. Children, 11(1), 97. https://doi.org/10.3390/children11010097

Laborie, L. B., Rosendahl, K., Dhouib, A., Simoni, P., Tomà, P., & Offiah, A. C. (2023). The effect of selective ultrasound screening on the incidence of late presentation of developmental hip dysplasia: A meta-analysis. Pediatric Radiology, 53(10), 1977–1988. https://doi.org/10.1007/s00247-023-05666-x

Lowry, C. A., Donoghue, V. B., & Murphy, J. F. (2005). Auditing hip ultrasound screening of infants at increased risk of developmental dysplasia of the hip. Archives of Disease in Childhood, 90(6), 579–581. https://doi.org/10.1136/adc.2004.052274

Lussier, E. C., Sun, Y. T., Chen, H. W., Chang, T. Y., & Chang, C. H. (2019). Ultrasound screening for developmental dysplasia of the hip after 4 weeks increases exam accuracy and decreases follow-up visits. Pediatrics and Neonatology, 60(3), 270–277. https://doi.org/10.1016/j.pedneo.2018.07.008

Nicholson, A., Dunne, K., Taaffe, S., Sheikh, Y., & Murphy, J. (2023). Developmental dysplasia of the hip in infants and children. BMJ, 383, e074507. https://doi.org/10.1136/bmj-2022-074507

Norlén, S., & Faergemann, C. (2022). Developmental dysplasia of the hip in infants referred for a combined pediatric orthopedic and radiologic examination: A prospective cohort study. Journal of Orthopaedics, 32, 109–114. https://doi.org/10.1016/j.jor.2022.05.014

O’Beirne, J. G., Chlapoutakis, K., Alshryda, S., Aydingoz, U., Baumann, T., Casini, C., de Pellegrin, M., Domos, G., Dubs, B., Hemmadi, S., Karantanas, A., Kolovos, S., Kraus, T., Zhao, L., Maizen, C., Mehdizadeh, M., Molitorisz, D., Persaud, T., Petratos, D., Placzek, R., Placzek, S., Scott, S., Schmid, R., Tarrant, A., & Voulgaris, K. (2019). International interdisciplinary consensus meeting on the evaluation of developmental dysplasia of the hip. Ultraschall in der Medizin – European Journal of Ultrasound, 40(4), 454–464. https://doi.org/10.1055/a-0924-5491

Pediatric Orthopaedic Society of North America. (2015). Swaddling and developmental hip dysplasia [Position statement]. Issued jointly with the International Hip Dysplasia Institute, the American Academy of Orthopaedic Surgeons, the United States Bone and Joint Initiative, and Shriners Hospitals for Children. https://posna.org/POSNA/media/Documents/Position%20Statements/SwaddlingPositionStatementApril2015.pdf

Shaw, B. A., & Segal, L. S. (2016). Evaluation and referral for developmental dysplasia of the hip in infants. Pediatrics, 138(6), Article e20163107. https://doi.org/10.1542/peds.2016-3107

Smart, L., Cundy, W., Williams, N., Arnold, A., Childs, J., Pelentsov, L., & Esterman, A. (2024b). Screening accuracy for developmental dysplasia of the hip by child health nurses. Children, 11(8), 915. https://doi.org/10.3390/children11080915

Smart, L., Pelentsov, L., Childs, J., Williams, N., & Esterman, A. (2024a). Nurses assessment of development hip dysplasia: A scoping review. Journal of Child Health Care, 28(1), 132–149. https://doi.org/10.1177/13674935221095647

St George, J., Kulkarni, V., Bellemore, M., Little, D. G., & Birke, O. (2020). Importance of early diagnosis for developmental dysplasia of the hip: A 5-year radiological outcome study comparing the effect of early and late diagnosis. Journal of Paediatrics and Child Health, 57(1), 41–45. https://doi.org/10.1111/jpc.15111

Tan, S. H. S., Lim, J. X. Y., Lim, A. K. S., & Hui, J. H. P. (2023). Risk factors for a false-negative Ortolani and Barlow examination in developmental dysplasia of the hip. Orthopaedics & Traumatology: Surgery & Research, 110(4), 103796. https://doi.org/10.1016/j.otsr.2023.103796

Tirta, M., Rahbek, O., Kold, S., & Husum, H.-C. (2025). Risk factors for developmental dysplasia of the hip before 3 months of age: A meta-analysis. JAMA Network Open, 8(1), Article e2456153. https://doi.org/10.1001/jamanetworkopen.2024.56153

Vaidya, S., Aroojis, A., & Mehta, R. (2021). Developmental dysplasia of hip and post-natal positioning: Role of swaddling and baby-wearing. Indian Journal of Orthopaedics, 55(6), 1410–1416. https://doi.org/10.1007/s43465-021-00513-3

Yoshioka-Maeda, K., Matsumoto, H., Honda, C., Kinjo, T., Aoki, K., Hattori, T., Okada, K., Shirouchi, M., Shiomi, M., Hosoya, N., & Fujiwara, K. (2025). Integrating web-based and objective structured clinical examination training programs for nurses on ultrasound hip screening during neonatal and infant home visits: A case study. BMC Medical Education, 25(1), 1007. https://doi.org/10.1186/s12909-025-07519-7

Yoshioka-Maeda, K., Matsumoto, H., Honda, C., Kinjo, T., Aoki, K., Hattori, T., Okada, K., Shirouchi, M., Shiomi, M., Hosoya, N., & Fujiwara, K. (2025). Integrating web-based and objective structured clinical examination training programs for nurses on ultrasound hip screening during neonatal and infant home visits: A case study. BMC Medical Education, 25, Article 1007. https://doi.org/10.1186/s12909-025-07519-7

Yoshioka-Maeda, K., Matsumoto, H., Honda, C., Kinjo, T., Aoki, K., Okada, K., Shirouchi, M., Shiomi, M., Hosoya, N., Fujiwara, K., & Hattori, T. (2026a). Association of objective structured clinical examination performance on nurse-led hip ultrasound imaging success: A prospective cohort study. International Journal of Nursing Studies Advances, 10, Article 100449. https://doi.org/10.1016/j.ijnsa.2025.100449

Yoshioka-Maeda, K., Matsumoto, H., Honda, C., Kinjo, T., Aoki, K., Okada, K., Shirouchi, M., Shiomi, M., Hosoya, N., & Hattori, T. (2026b). Evaluating the implementation of nurse-led community-based ultrasound screening for developmental dysplasia of the hip in Japan: A mixed methods RE-AIM study. International Journal of Nursing Studies. https://doi.org/10.1016/j.ijnurstu.2026.105552

Yoshioka-Maeda, K., Matsumoto, H., Inagaki-Asano, A., & Honda, C. (2023). Community-based hip screening for up to four-month-old infants and health guidance for their caregivers in Japan: A nation-wide survey. Nursing Reports, 13(4), 1442–1451. https://doi.org/10.3390/nursrep13040121

Published

30-07-2026

How to Cite

Abdulkareem Ibrahim, S. ., Abdullah Garjees, N. ., Ismael Ibrahim, M. ., Abdallah Mohamed, D. ., Abdi Hasan, J. ., & Hashem Salloum, K. . (2026). Diagnostic Accuracy of Clinical Examination, Ultrasonography, and Radiography for Developmental Dysplasia of the Hip in Infants: A Prospective Diagnostic-Accuracy Cohort Study. The Malaysian Journal of Nursing (MJN), 18(1), 150-161. https://doi.org/10.31674/mjn.2026.v18i01.014

Metrics