Nurse-Led Interventions in the Comprehensive Management of Patients Undergoing Percutaneous Coronary Intervention (PCI): A Systematic Review

Authors

DOI:

https://doi.org/10.31674/mjn.2026.v17i05.017

Abstract

Background: Nurses play an important role in monitoring and early detection of complications, as well as in managing patients after Percutaneous Coronary Intervention (PCI) to improve clinical outcomes. Previous randomized reviews have mainly focused on physician-led or multidisciplinary PCI care, with limited attention to nurse-led management. Therefore, this review evaluated whether nurse-led interventions across the PCI care continuum provide additional clinical and patient-reported benefits compared with usual care. Methods: This study employed systematic review design and was conducted using four databases: ProQuest, ScienceDirect, EBSCO, and PubMed. The PICO framework was adopted to guide the search strategy, and the PRISMA guidelines were followed. All selected articles were assessed in terms of quality using the Joanna Briggs Institute critical appraisal tools. Results: Based on the search results, 1,412 articles were identified. After removal of duplicates and screening of titles, abstracts, and full texts, 25 articles were included in the final synthesis, comprising 7 articles from ScienceDirect, 14 articles from ProQuest, 2 articles from EBSCO, and 2 articles from PubMed. These articles consisted of randomized controlled trials, cohort studies, and cross-sectional studies. They were categorized into interventions during assessment, pre-PCI procedures, post-PCI procedures, and follow-up care and rehabilitation. Conclusion: This study shows that structured, evidence-based nurse-led interventions significantly improve outcomes in patients undergoing PCI. The findings demonstrated that this model generated was associated with low Major Adverse Cardiovascular Events (MACE) (1.52%) and mortality (0.46%) through structured assessment, reduced anxiety, enhanced procedural readiness (p < 0.05), improved self-care behaviors (p < 0.05), and promotion of recovery and quality of life. Further multicenter studies with long-term follow-up are recommended to validate and generalize these findings across diverse healthcare settings.

Keywords:

Coronary Heart Disease, Nurse-Led, Nursing Practice, Percutaneous Coronary Intervention

Downloads

Download data is not yet available.

References

Alzhanova, A., Schadewaldt, V., Hendriks, J. M., & Schultz, T. J. (2026). Effectiveness of nurse-led clinics for patients with coronary heart disease: A systematic review and meta-analysis. European Journal of Cardiovascular Nursing, 2025, 1–15. https://doi.org/10.1093/eurjcn/zvaf207

Asgari, M. R., Vafaei-Moghadam, A., Babamohamadi, H., Ghorbani, R., & Esmaeili, R. (2020). Comparing acupressure with aromatherapy using Citrus aurantium in terms of their effectiveness in sleep quality in patients undergoing percutaneous coronary interventions: A randomized clinical trial. Complementary Therapies in Clinical Practice, 38, 101066. https://doi.org/10.1016/j.ctcp.2019.101066

Bernal-Jiménez, M. Á., Calle, G., Barrios, A. G., Gheorghe, L. L., Cruz-Cobo, C., Trujillo-Garrido, N., Rodríguez-Martín, A., Tur, J. A., Vázquez-García, R., & Santi-Cano, M. J. (2024). Effectiveness of an interactive mHealth app (EVITE) in improving lifestyle after a coronary event: Randomized controlled trial. JMIR mHealth and uHealth, 12. https://doi.org/10.2196/48756

Cao, J., Sun, P., Zhang, L., Chen, X., Gui, W., Ou, A., Chen, K., & Ma, L. (2022). Effects of acceptance and commitment therapy on self-management skills and psychological resilience of young and middle-aged patients undergoing percutaneous transluminal coronary intervention for primary myocardial infarction: A pilot study. Trials, 23(1), 32. https://doi.org/10.1186/s13063-021-05923-0

Chang, Z., Guo, A., Zhou, A., Sun, T., Ma, L., Gardiner, F. W., & Wang, L. (2020). Nurse-led psychological intervention reduces anxiety symptoms and improves quality of life following percutaneous coronary intervention for stable coronary artery disease. Australian Journal of Rural Health, 28(2), 124–131. https://doi.org/10.1111/ajr.12587

Chao, L., & Li, G. (2024). Application of predictive nursing based on EuroSCORE in perioperative period of PCI. Alternative Therapies in Health and Medicine, 30(1), 51–57. https://www.alternative-therapies.com/pdfarticles/9315.pdf

Corones-Watkins, K., Cooke, M., Theobald, K., White, K., Thompson, D. R., Ski, C. F., King-Shier, K., Conway, A., & Ramis, M.-A. (2021). Effectiveness of nurse-led clinics in the early discharge period after percutaneous coronary intervention: A systematic review. Australian Critical Care, 34(5), 510–517. https://doi.org/10.1016/j.aucc.2020.10.012

Dai, L., Zhang, Q., Lu, F., Li, C., Shen, X., & Xu, H. (2024). Influence of rehabilitation training-based procedural follow-up on pulmonary function and quality of life in patients undergoing coronary angiography and stenting. Alternative Therapies in Health and Medicine, 30(11), 422–428.

Dong, L., Lu, C., Wensen, C., Fuzhong, C., Khalid, M., Xiaoyu, D., Guangjuan, L., Yanxia, Q., Yufeng, Z., Xinjian, L., Leilei, C., & Junhong, W. (2022). Performance of PRECISE-DAPT and age–bleeding–organ dysfunction score for predicting bleeding complications during dual antiplatelet therapy in Chinese elderly patients. Frontiers in Cardiovascular Medicine, 9, 1–9. https://doi.org/10.3389/fcvm.2022.910805

Fan, Y., & Lin, X. (2025). Application of perioperative comprehensive care in coronary heart disease patients undergoing coronary stent implantation: A study on the collaboration of cardiology operating room nursing. Journal of Multidisciplinary Healthcare, 18, 3423–3431. https://doi.org/10.2147/JMDH.S527597

Fan, Y., & Zhou, X. (2025). Application of the plan–do–check–action cycle in reducing the incidence of forearm hematoma in patients after transradial artery percutaneous coronary interventions. Journal of Multidisciplinary Healthcare, 18, 1183–1189. https://doi.org/10.2147/JMDH.S511825

Fu, H., Zhou, G., Wang, M., & Chen, Y. (2025). Research on internet plus continuing nursing under dual heart medical model after percutaneous coronary intervention. Medicine, 104(24), e42778. https://doi.org/10.1097/MD.0000000000042778

Galli, M., Laborante, R., Andreotti, F., Vergallo, R., Montone, R. A., Iaconelli, A., Trani, C., Burzotta, F., Crea, F., & D’Amario, D. (2022). Bleeding complications in patients undergoing percutaneous coronary intervention. Reviews in Cardiovascular Medicine, 23(8). https://doi.org/10.31083/j.rcm2308286

Guo, L., Gao, W., Wang, T., & Shan, X. (2023). Effects of empowerment education on patients after percutaneous coronary intervention: A meta-analysis and systematic review. Medicine, 102(23), e33992. https://doi.org/10.1097/MD.0000000000033992

Hosseini, M.-S., Jahanshahlou, F., Akbarzadeh, M. A., Zarei, M., & Vaez-Gharamaleki, Y. (2024). Formulating research questions for evidence-based studies. Journal of Medicine, Surgery, and Public Health, 2, 100046. https://doi.org/10.1016/j.glmedi.2023.100046

Ibrahim, A., Chongprasertpon, N., Heelan, M., Maguire, I. C., Coffey, J., McElligott, H., Cahill, C., Mannix, K., Ahern, C., McDermott, B., Hennessy, T. G., Arnous, S., & Kiernan, T. J. (2019). Outcomes of nurse-led clinic for patients treated with percutaneous coronary intervention: A retrospective analysis. Applied Nursing Research, 49, 19–22. https://doi.org/10.1016/j.apnr.2019.07.005

Ister, D., & Altinbas, Y. (2022). Effect of acupressure on the blood pressure, heart rate, and pain severity of patients who underwent coronary angiography: a randomized controlled trial. Alternative Therapies in Health and Medicine, 29(7), 216–221. https://www.alternative-therapies.com/pdfarticles/69641.pdf

Jiang, W., Feng, M., Gao, C., Li, J., Gao, R., & Wang, W. (2020). Effect of a nurse-led individualized self-management program for Chinese patients with acute myocardial infarction undergoing percutaneous coronary intervention. European Journal of Cardiovascular Nursing, 19(4), 320–329. https://doi.org/10.1177/1474515119889197

Kandaswamy, E., & Zuo, L. (2018). Recent advances in treatment of coronary artery disease: Role of science and technology. International Journal of Molecular Sciences, 19(2), 424. https://doi.org/10.3390/ijms19020424

Oshvandi, K., Movaheditabar, E., Naghshtabrizi, B., Mohammadi, Y., & Shamsizadeh, M. (2021). The effect of video-based educational program on satisfaction and comfort in patients undergoing transradial coronary angiography: A single-blinded randomized controlled trial. Journal of Vascular Nursing, 39(2), 27–32. https://doi.org/10.1016/j.jvn.2021.01.001

Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., & Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71

Peng, X., Zhang, J., Wan, L., Wang, H., & Zhang, W. (2022). The effect of a seven-step rehabilitation training program on cardiac function and quality of life after percutaneous coronary intervention for acute myocardial infarction. Pakistan Journal of Medical Sciences, 38(1), 123. https://doi.org/10.12669/pjms.38.1.4945

Premkumar, S., Ramamoorthy, L., & Pillai, A. (2022). Impact of nurse-led cardiac rehabilitation on patients’ behavioral and physiological parameters after a coronary intervention: A pilot randomized controlled trial. Journal of Family and Community Medicine, 29(1), 17. https://doi.org/10.4103/jfcm.jfcm_315_21

Price, A. L., Amin, A. P., Rogers, S., Messenger, J. C., Moussa, I. D., Miller, J. M., & Rao, S. V. (2024). Implementation of a multidimensional strategy to reduce post-PCI bleeding risk. Circulation: Cardiovascular Interventions, 17(3), e013003. https://doi.org/10.1161/CIRCINTERVENTIONS.123.013003

Qi, P., Soh, P., Hao, W., Wong, T., Roy, T., Wai, W., & Tam, S. (2024). Effectiveness of non-pharmacological interventions in improving sleep quality after cardiac surgery: A systematic review and meta-analysis. Journal of Clinical Nursing, 33, 2084–2098. https://doi.org/10.1111/jocn.17115

Qiu, X. (2024). Nurse-led intervention in the management of patients with cardiovascular diseases: A brief literature review. BMC Nursing, 23(1), 1–9. https://doi.org/10.1186/s12912-023-01422-6

Qiu, X., & Ren, S. (2025). Effectiveness of integrated nurse-physician management in post-PCI coronary heart disease patients: an analysis based on follow-up data. Frontiers in Cardiovascular Medicine, 12, 1571953. https://doi.org/10.3389/fcvm.2025.1571953

Rejeh, N., Tadrisi, S. D., Yazdani, S., Saatchi, K., & Vaismoradi, M. (2020). The effect of hand reflexology massage on pain and fatigue in patients after coronary angiography: A randomized controlled clinical trial. Nursing Research and Practice, 2020. https://doi.org/10.1155/2020/8386167

Rostami, K., Maryami, M., & Rambod, M. (2023). The effect of telephone counseling based on Orem's model on adherence to treatment and resilience of patients with coronary angioplasty: a randomized clinical trial. BMC cardiovascular disorders, 23(1), 489. https://doi.org/10.1186/s12872-023-03529-9

Sallal, M. H., & Mousa, M. A. (2023). Reduction of pain intensity for patients undergoing arterial sheath removal after coronary artery angioplasty: An interventional program. Revista Latinoamericana de Hipertension, 18(5), 202. https://doi.org/10.5281/zenodo.8364436

Sarabi, H. N., Farsi, Z., Butler, S., & Pishgooie, A. H. (2021). Comparison of the effectiveness of position change for patients with pain and vascular complications after transfemoral coronary angiography: A randomized clinical trial. BMC Cardiovascular Disorders, 21, 1–10. https://doi.org/10.1186/s12872-021-01922-w

Shanmugalakshmi, A., Micheal, M. V., & Madhavi, S. (2023). Effectiveness of educational intervention on knowledge on self-care practices following percutaneous coronary interventions. Cardiometry, 26, 499–502. https://doi.org/10.18137/cardiometry.2023.26.499502

Shi, Y.-J., Liu, Y., Jiang, T.-T., Zhang, H.-R., & Shi, T.-Y. (2022). Effects of multidisciplinary exercise management on patients after percutaneous coronary intervention: A randomized controlled study. International Journal of Nursing Sciences, 9(3), 286–294. https://doi.org/10.1016/j.ijnss.2022.06.012

Sokhanvar, S., Tirgari, B., Forouzi, M. A., Salari, M., & Jahani, Y. (2023). Effect of ice bag application to femoral region on pain and vital signs in patients with acute myocardial infarction undergoing percutaneous coronary intervention: A randomized controlled trial. The Open Nursing Journal, 17(1), 1–9. https://doi.org/10.2174/18744346-v17-e230113-2022-133

Türen, S., Yilmaz, R. A., Yesiltepe, N., & Bektas, I. (2022). Effect of the head of bed elevation on back pain after elective coronary angiography: A randomized controlled trial. Applied Nursing Research, 64, 151571. https://doi.org/10.1016/j.apnr.2022.151571

Tursi, E. A., Rana, B. M., Morgan, K. M., & Schafranek, W. (2025). Implementation of an Elective PCI Patient Risk Assessment and Exclusion Criteria Tool. Case Reports, 30(35), 105154. https://doi.org/10.1016/j.jaccas.2025.105154

Uhm, I. A., & Hwang, S. Y. (2023). Effect of risk factor-tailored autonomy enhancement education in first-time middle-aged patients undergoing percutaneous coronary intervention: A randomized controlled trial. BMC Nursing, 22(1), 1–11. https://doi.org/10.1186/s12912-023-01654-6

Wihastuti, T. A., Candra, Y., Dewi, S., & Kumboyono, K. (2019). Collaboration between doctors and nurses in the care of acute coronary syndrome patients at emergency departments from the nurses’ perspective. Journal of Interprofessional Education & Practice, 15, 20–23. https://doi.org/10.1016/j.xjep.2019.01.006

Xia, C., Zheng, Y., Ji, L., & Liu, H. (2024). Comparative effectiveness of different interventions on adherence to exercise-based cardiac rehabilitation among patients after percutaneous coronary intervention: A network meta-analysis of randomized controlled trials. BMC Nursing, 23, 1–12. https://doi.org/10.1186/s12912-024-02561-0

Xu, W., Tu, H., Xiong, X., Peng, Y., & Cheng, T. (2022). Predicting the risk of unplanned readmission at 30 days after PCI: Development and validation of a new predictive nomogram. Clinical Interventions in Aging, 17, 1013–1023. https://doi.org/10.2147/CIA.S369885

Yang, J., Gao, Y., Yu, C. P., Zhang, B., Zou, L. J., & Yan, Z. (2026). Nurse-led intervention versus usual care on cardiovascular risk factors in patients with coronary artery disease: A meta-analysis including randomized and observational studies. BMC Cardiovascular Disorders 26, 39(2026). https://doi.org/10.1186/s12872-025-05428-7

Zhang, T., & Qi, X. (2021). Greater nursing role for enhanced post-percutaneous coronary intervention management. International Journal of General Medicine, 14, 7115–7120. https://doi.org/10.2147/IJGM.S337385

Zhao, W., Zhao, W., & Sun, X. (2025). Impact of nurse-led cardiovascular risk assessment and management program on 1-year outcomes in patients on hemodialysis post percutaneous coronary intervention. The Journal of Cardiovascular Nursing, 41(3), 209-216. https://doi.org/10.1097/JCN.0000000000001234

Published

25-05-2026

How to Cite

Naja, F., Kumboyono, K. ., & Kristianto, H. . (2026). Nurse-Led Interventions in the Comprehensive Management of Patients Undergoing Percutaneous Coronary Intervention (PCI): A Systematic Review. The Malaysian Journal of Nursing (MJN), 17(5), 177-188. https://doi.org/10.31674/mjn.2026.v17i05.017

Metrics