Pharmacology and Pharmacokinetics in Oral and Maxillofacial Surgery: A Comprehensive Review
DOI:
https://doi.org/10.31674/ijfdc.2025.v1i02.003Abstract
Abstract
Oral and maxillofacial surgery (OMFS) is a specialized surgical discipline that demands a profound understanding of pharmacology and pharmacokinetics. This comprehensive review highlights the critical role of these principles in optimizing patient care and minimizing risks within the unique physiological and pathological context of the head and neck region. While general surgical pharmacology is well-documented, the specific nuances of drug selection, dosing, and potential interactions in OMFS patients—who often present with complex medical histories, localized infections, and significant pain management challenges—warrant dedicated attention. This paper integrates fundamental drug principles with patient-specific considerations, covering local anesthetics, analgesics, antibiotics, corticosteroids, sedatives, and emergency medications. It further delves into crucial aspects such as drug interactions, toxicity, allergic reactions, and the necessity of appropriate laboratory investigations. Drawing from innovations stemming from the industrial era, which revolutionized drug synthesis, understanding of pharmacokinetics, and aseptic techniques, this review provides OMFS practitioners with an updated, robust framework. The aim is to ensure optimal therapeutic outcomes, enhance patient safety, and guide rational prescribing in a rapidly evolving healthcare landscape, emphasizing the shift towards personalized and evidence- based pharmacological interventions.
Keywords: Antibiotics, Analgesics, Anti-inflammatory drugs, NSAIDs, Steroids.
Keywords:
Antibiotics, Analgesics, Anti-inflammatory drugs, NSAIDs, SteroidsDownloads
References
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