Herbal Functional Foods: Traditional Uses and Modern Scientific Evidence

Authors

  • Mst Sharmin Khatun Masters of pharmacy
  • Sreemoy kanti Das Deputy Deen
  • Mohammad Gousuddin

DOI:

https://doi.org/10.31674/ijbb.2025.v02i02.004

Abstract

Herbal functional foods represent a unique intersection between traditional medicine and modern nutritional science. These foods, derived from medicinal plants, have long been used in various cultural systems such as Ayurveda, Traditional Chinese Medicine (TCM), and indigenous healing practices for their health-promoting properties. In recent decades, scientific research has begun to validate many of these traditional claims, revealing bioactive compounds responsible for a range of physiological benefits including antioxidant, anti-inflammatory, immunomodulatory, and cardioprotective effects. This review explores the traditional uses of prominent herbal functional foods such as turmeric, ginger, garlic, ginseng, and holy basil, and examines contemporary scientific studies that support their efficacy and mechanisms of action. Additionally, the article discusses the challenges related to safety, standardization, and regulatory approval, while highlighting the potential of these herbs in the prevention and management of chronic diseases. The integration of traditional knowledge with modern scientific validation provides a promising foundation for the future of functional nutrition and evidence-based herbal therapeutics.

Keywords:

Herbal Functional Foods, Traditional Medicine, Phytochemicals, Scientific Evidence, Bioactive Compounds

References

Amagase, H. (2006). Clarifying the real bioactive constituents of garlic. The Journal of Nutrition, 136(3 Suppl), 716S–725S. https://doi.org/10.1093/jn/136.3.716S

Aggarwal, B. B., Sundaram, C., Malani, N., & Ichikawa, H. (2007). Curcumin: The Indian solid gold. Advances in Experimental Medicine and Biology, 595, 1–75. https://doi.org/10.1007/978-0-387-46401-5_1

Ammon, H. P., & Wahl, M. A. (1991). Pharmacology of Curcuma longa. Planta Medica, 57(01), 1–7. https://doi.org/10.1055/s-2006-960004

Bertoncini-Silva, C., Vlad, A., Ricciarelli, R., Fassini, P. G., Suen, V. M. M., & Zingg, J.-M. (2024). Enhancing the bioavailability and bioactivity of curcumin for disease prevention and treatment. Antioxidants, 13 (3), 331. https://doi.org/10.3390/antiox13030331(2).

Bischoff-Kont, I., & Fürst, R. (2021). Benefits of ginger and its constituent 6-shogaol in inhibiting inflammatory processes. Pharmaceuticals, 14 (6), 571. https://doi.org/10.3390/ph14060571[](https://www.mdpi.com/1424-8247/14/6/571 “1”)

Christensen, L. P. (2009). Ginsenosides: Chemistry, biosynthesis, analysis, and potential health effects. Advances in Food and Nutrition Research, 55, 1–99. https://doi.org/10.1016/S1043-4526(08)00401-4

Cheng, A. L., et al. (2001). Pharmacokinetics of curcumin: Studies in normal volunteers. Cancer Chemotherapy and Pharmacology, 47(4), 337-341.

EFSA (2011). Scientific opinion on the substantiation of health claims related to medicinal plants. EFSA Journal, 9(12), 2533-2541.

El-Saadony, M. T., Saad, A. M., Korma, S. A., Salem, H. M., Abd El-Mageed, T. A., Alkafaas, S. S., Elsalahaty, M. I., Elkafas, S. S., Mosa, W. F. A., Ahmed, A. E., Mathew, B. T., Albastaki, N. A., Alkuwaiti, A. A., El-Tarabily, M. K., AbuQamar, S. F., El-Tarabily, K. A., & Ibrahim, S. A. (2024). Garlic bioactive substances and their therapeutic applications for improving human health: A comprehensive review. Frontiers in Immunology, 15 , 1277074. https://doi.org/10.3389/fimmu.2024.1277074(2).

El-Sohaimy, S. A., & Hussain, M. A. (2023). Functional probiotic foods development: Trends, concepts, and products. Fermentation, 9 (3), 249. https://doi.org/10.3390/fermentation9030249[](https://www.mdpi.com/2311-5637/9/3/249.

Etkin, N. L. (2006). (PAGE) Edible Medicines: An Ethnopharmacology of Food. University of Arizona Press.

Harrison, R., et al. (2015). Effect of garlic on blood pressure: A systematic review and meta-analysis. The Journal of Clinical Hypertension, 15(8), 626-636.

Haller, C. A., & Benowitz, N. L. (2009). Adverse drug reactions to herbal products. The American Journal of Medicine, 122(7), 589-595.

Hewlings, S. J. (2017). Curcumin: The science behind its effects on inflammation, cancer, and other diseases. Phytotherapy Research, 31(5), 825-835.

Jamshidi, N., & Cohen, M. M. (2017). The clinical efficacy and safety of Tulsi in humans: A systematic review of the literature. Evidence-Based Complementary and Alternative Medicine, 2017, Article ID 9217567. https://doi.org/10.1155/2017/9217567.

Kim, H. G., Cho, J. H., Yoo, S. R., Lee, J. S., Han, J. M., Lee, N. H., & Son, C. G. (2013). Antifatigue effects of Panax ginseng C.A. Meyer: A randomized, double-blind, placebo-controlled trial. PLoS ONE, 8(4), e61271. https://doi.org/10.1371/journal.pone.0061271

Kumar, A., Tyagi, D., & Choudhary, A. (2017). Curcuma longa: Traditional uses and recent advances—An overview. International Journal of Green Pharmacy, 11(3), S475–S483.

Lee, Y. H., et al. (2011). Effectiveness of ginger for osteoarthritis pain and disability: A systematic review. The Journal of Pain, 12(11), 1185-1191.

Leonti, M. (2011). The future is written: Impact of scripts on the cognition, selection, knowledge and transmission of medicinal plant use and its implications for ethnobotany and ethnopharmacology. Journal of Ethnopharmacology, 134(3), 542–555. https://doi.org/10.1016/j.jep.2011.01.017.

Liao, F., et al. (2012). Ginseng improves insulin sensitivity in human studies: A systematic review. American Journal of Clinical Nutrition, 95(5), 1223-1233.

Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews, 4(8), 118–126. https://doi.org/10.4103/0973-7847.70902

Madaan, S. (2025). Clinical insights into the immunomodulatory effects of Tulsi (Holy Basil). International Research Journal of Modern Engineering & Technology Studies, 1 (1), 1–10. https://doi.org/10.56726/IRJMETS66839(3).

Mahomoodally, M. F. (2013). Ginger and its bioactive components: A review of their antioxidant, anti-inflammatory, and metabolic effects. Journal of Medicinal Food, 16(6), 482-489.

Mondal, S., Mirdha, B. R., & Mahapatra, S. C. (2009). The science behind the sacredness of Tulsi (Ocimum sanctum Linn.). Indian Journal of Physiology and Pharmacology, 53(4), 291–306.

Nasri, H., Baradaran, A., Shirzad, H., & Rafieian-Kopaei, M. (2014). New concepts in nutraceuticals as an alternative to pharmaceuticals. International Journal of Preventive Medicine, 5(12), 1487–1499.

Pattanayak, P., Behera, P., Das, D., & Panda, S. K. (2010). Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview. Pharmacognosy Reviews, 4(7), 95–105. https://doi.org/10.4103/0973-7847.65323

Patwardhan, B., Warude, D., Pushpangadan, P., & Bhatt, N. (2005). Ayurveda and traditional Chinese medicine: a comparative overview. Evidence-Based Complementary and Alternative Medicine, 2(4), 465–473. https://doi.org/10.1093/ecam/neh140.

Rahman, K., & Lowe, G. M. (2006). Garlic and cardiovascular disease: A critical review. The Journal of Nutrition, 136(3 Suppl), 736S–740S. https://doi.org/10.1093/jn/136.3.736S.

Reay, J. L., Kennedy, D. O., & Scholey, A. B. (2005). Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of Psychopharmacology, 19(4), 357–365. https://doi.org/10.1177/0269881105053305

Ried, K., et al. (2013). Effect of garlic on blood pressure: A systematic review and meta-analysis. The Journal of Clinical Hypertension, 15(8), 626-636.

Sharma, P. V. (2005). Dravyaguna Vijnana: Materia Medica – Vegetable Drugs (Vol. 2). Chaukhambha Bharati Academy.

Talib, W. H., Atawneh, S., Shakhatreh, A. N., Shakhatreh, G. N., Rasheed aljarrah, I. S., Hamed, R. A., Adel Banyyounes, D., & Al-Yasari, I. H. (2024). Anticancer potential of garlic bioactive constituents: Allicin, Z-ajoene, and organosulfur compounds. Pharmacia, 71 (1), 1–23. https://doi.org/10.3897/pharmacia.71.e114556(1).

Vohra, S. R., et al. (2013). National policy on medicinal plants and herbal industry in India: Regulatory framework. Indian Journal of Pharmaceutical Sciences, 75(2), 168-174

White, B. (2007). Ginger: An overview. American Family Physician, 75(11), 1689–1691.

Wang, J., van der Heijden, R., Spruit, S., Hankermeier, T., Chan, K., van der Greef, J., & Wang, M. (2012). Quality and safety of Chinese herbal medicines guided by a systems biology perspective. Journal of Ethnopharmacology, 140(3), 594–602. https://doi.org/10.1016/j.jep.2012.01.064

Wang, J., Sun, B., Cao, Y., Tian, Y., & Li, X. (2018). Antioxidant and anti-inflammatory activities of functional beverages containing herbal ingredients: A review. Food Chemistry, 261, 262–270. https://doi.org/10.1016/j.foodchem.2018.04.073

Xie, Y., et al. (2015). Antioxidant and anti-inflammatory activities of ginger (Zingiber officinale) and its effects on metabolic diseases. Frontiers in Pharmacology, 6, 1-7.

Yuan, H., Ma, Q., Ye, L., & Piao, G. (2012). The traditional medicine and modern medicine from natural products. Molecules, 21(5), 559. https://doi.org/10.3390/molecules21050559

Zeng, Y., et al. (2015). Curcumin and turmeric: Biological effects, potential applications in chronic diseases, and regulatory issues. International Journal of Food Science & Technology, 50(5), 1272-1283.

Zhang, A., Sun, H., Wang, X., Han, Y., & Wang, P. (2015). Modern analytical techniques in metabolomics analysis. The Analyst, 140(3), 627–639. https://doi.org/10.1039/C4AN01092E

Zhou, Y. X., & Huang, Y. (2017). Traditional uses, phytochemistry and pharmacological properties of Zingiber officinale (Ginger): A review. Natural Product Communications, 12(3), 299–308.

Published

27-08-2025

How to Cite

Khatun, M. S., Sreemoy kanti Das, & Mohammad Gousuddin. (2025). Herbal Functional Foods: Traditional Uses and Modern Scientific Evidence. International Journal of Biotechnology and Biomedicine (IJBB), 2(2), 39-54. https://doi.org/10.31674/ijbb.2025.v02i02.004

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