• Hemapriyaa Vijayan Faculty of Applied Science, Lincoln University College, Malaysia


Cosmeceuticals   are   topical   cosmetic   pharmaceutical   preparations   which   are used to enhance the beauty through ingredients that provide additional health-related function or benefit. Natural colorants are dyes and pigmentary molecules which are extracted from nature sources such as minerals, plants and animals. A total of six plants were   selected   as   potential   candidates   for   this   project   namely Punica granatum, Dicranopteris linearis, Tagetes erecta, Hibiscus rosa sinensis (red and yellow) and Hibiscus schizopethalus. Plant samples which were freeze-dried and oven-dried were extracted   using   absolute   methanol   and   subjected   to   rotary   evaporation. For the preparation of boiled extracts, samples were boiled with distilled water for an hour prior   to   freeze   drying.   All   the extracts   exerted no damage to RAW   264.7 murine macrophage cell line with IC50 values more than 100 µg/ml, which was the highest concentration tested in the current study using MTT assay. A total of three species of skin bacteria namely Staphylococcus aureus (five isolates: Sa1, Sa2, Sa3, Sa4, Sa5), Staphylococcus epidermidis (five   isolates:   Se1,   Se2,   Se3,   Se4,   Se5)   and Chryseobacterium aquifrigindense (five   isolates:   Ca1,   Ca2,   Ca3,   Ca4,   Ca5)   were isolated from the skin swabs of thirty subjects with skin infection. From the results obtained   from   anti-skin   bacterial   testing   using   disc   diffusion   method,   the   extracts inhibited Staphylococcus aureus and Staphylococcus epidermidis but did not show any anti-bactericidal activity towards Chryseobacterium aquifrigindense. The highest anti-skin bacterial activity was shown by Dicranopteris linearis (oven-dried) and Punica granatum (freeze-dried and oven-dried)   extracts.   In conclusion, these extract   have potential to inhibit the growth of skin bacteria without causing toxicity towards the skin.


Anti skin bacteria, Cosmeceutical, Natural colorant extract


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How to Cite

Vijayan , H. . (2024). ANTI SKIN BACTERIA ACTIVITY OF SELECTED PLANTS IN MALAYSIA. International Journal of Biotechnology and Biomedicine (IJBB), 1(1), 72-88. Retrieved from