Optic Neuritis: Evaluation of Visual Acuity and Contrast Sensitivity. A Hospital Based Cross Sectional Study

Authors

  • Syed Barkar Islam Department of Vision Sciences University of Lahore, Lahore Campus, Punjab 54770, Pakistan
  • Mutahir Shah Tertiary Care General Hospital Islamabad, Muhammad Tufail Niazi Rd,Mauve Area G 9/1, Islamabad, Islamabad Capital Territory 44000, Pakista
  • Sikandar Abbas Department of Vision Sciences University of Lahore, Lahore Campus, Punjab 54770, Pakistan
  • Saif Ullah Optometrist Al-Shifa Trust Eye Hospital Rawalpindi, Main G.T. Road, Near Ayub Park, Rawalpindi 44000, Punjab, Pakistan
  • Sufian Ali Khan Tertiary Care General Hospital Islamabad, Muhammad Tufail Niazi Rd, Mauve Area G 9/1, Islamabad, Islamabad Capital Territory 44000, Pakistan
  • Muneeb Ullah University of Montreal, Station Centre-ville, Montréal, Quebec H3C 0G4, Canada

DOI:

https://doi.org/10.31674/mjmr.2023.v07i02.005

Abstract

Objective: To assess visual acuity and contrast sensitivity in various form of Optic neuritis patients. Study Design and Settings: It was a hospital based cross sectional study conducted in eye department of Teaching hospital, University of Lahore Pakistan. Total duration of the study was 4 months from January 2022-April 2022. Methods: A total of 32 patients were included in the study. Purposive sampling technique was adopted for sampling. Patients age 15-45 were included in the study. A detailed eye examination was done in patients presented to eye department with pain and evaluated for optic neuritis, and demographics along with clinical signs and symptoms were documented using a proforma. Results: Total 32 patients were included in the study having Optic Neuritis. Mean age of the patients was 29 ±8.3SD (Range 15-45). The optic neuritis was divided into further sub-divisions, i.e. Pappilits 11 patients, Retrobulbar Neuritis 14 patients and neuroretinitis 7 patients. A paired t test comparing contrast sensitivity before and after treatment showed a significance of .03 improvement after treatment. In spite of the fact that the results demonstrated that contrast sensitivity did not return to normal, they did show that with prompt treatment, a substantial improvement in contrast sensitivity was possible. Same significance of .02 was found for improvement in VA post-operatively when a paired t test was applied. Conclusion:  Vision and contrast sensitivity both are affected in ON, however VA can be improved to normal vision after treatment, but contrast seldom improve to its normal value.

Keywords:

Contrast Sensitivity, Optic Neuritis, Vision

Downloads

Download data is not yet available.

Author Biography

Syed Barkar Islam, Department of Vision Sciences University of Lahore, Lahore Campus, Punjab 54770, Pakistan

Dept of Optometry

Asst Professor

References

Ambika, S., Padmalakshmi, K., Venkatraman, V., & Noronha, O. V. (2018). Visual outcomes and clinical manifestations of pediatric optic neuritis in Indian population: an institutional study. Journal of Neuro-Ophthalmology, 38(4), 462-465. https://doi.org/10.1097/WNO.0000000000000646

Asseyer, S., Asgari, N., Bennett, J., Bialer, O., Blanco, Y., Bosello, F., ... & Stiebel-Kalish, H. (2023). The Acute Optic Neuritis Network (ACON): Study protocol of a non-interventional prospective multicenter study on diagnosis and treatment of acute optic neuritis. Frontiers in Neurology, 14. https://doi.org/10.3389/fneur.2023.1102353

Backner, Y., Petrou, P., Glick-Shames, H., Raz, N., Zimmermann, H., Jost, R. & Levin, N. (2019). Vision and vision-related measures in progressive multiple sclerosis. Frontiers in Neurology, 10, 455. https://doi.org/10.3389/fneur.2019.00455

Bennett, J. L. (2019). Optic neuritis. Continuum (Minneapolis, Minn.), 25(5), 1236. https://doi.org/10.1212/CON.0000000000000768

Collorone, S., Prados, F., Kanber, B., Cawley, N. M., Tur, C., Grussu, F., ... & Toosy, A. T. (2021). Brain microstructural and metabolic alterations detected in vivo at onset of the first demyelinating event. Brain, 144(5), 1409-1421. https://doi.org/10.1093/brain/awab043

Huang, Y., Zhou, L., ZhangBao, J., Cai, T., Wang, B., Li, X., ... & Wang, M. (2019). Peripapillary and parafoveal vascular network assessment by optical coherence tomography angiography in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders. British Journal of Ophthalmology, 103(6), 789-796. http://dx.doi.org/10.1136/bjophthalmol-2018-312231

Kowsalya, A., Ramalingam, U., Chaudhary, S., & Kumar, M. (2023). Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study. Indian Journal of Ophthalmology, 71(2), 637-642. https://doi.org/10.4103/ijo.IJO_1407_22

Liberski, S., Kaluzny, B. J., & Kocięcki, J. (2022). Methanol-induced optic neuropathy: A still-present problem. Archives of Toxicology, 1-21. https://doi.org/10.1007/s00204-021-03202-0

Mahayana, I. T., Sakti, D. H., & Gani, T. T. (2022). Automated grating contrast-sensitivity: The easy test for hidden visual loss in recovered optic neuritis patient. Taiwan Journal of Ophthalmology, 12(3), 301. https://doi.org/10.4103/tjo.tjo_21_21

Morrow, S. A., Fraser, J. A., Day, C., Bowman, D., Rosehart, H., Kremenchutzky, M., & Nicolle, M. (2018). Effect of treating acute optic neuritis with bioequivalent oral vs intravenous corticosteroids: a randomized clinical trial. JAMA neurology, 75(6), 690-696. https://doi.org/10.1001/jamaneurol.2018.0024

Naumovska, M., Sheikh, R., Bengtsson, B., Malmsjö, M., & Hammar, B. (2018). Visual outcome is similar in optic neuritis patients treated with oral and iv high-dose methylprednisolone: a retrospective study on 56 patients. BMC neurology, 18(1), 1-7. https://doi.org/10.1186/s12883-018-1165-6

Oreja-Guevara, C., Quezada-Sánchez, J., Díaz-Díaz, J., Gómez-Estévez, I., & Suárez, E. A. (2022). Analysis of Visual Acuity, Contrast Sensitivity and Color Perception in Multiple Sclerosis Patients. Multiple Sclerosis and Related Disorders, 59. https://doi.org/10.1016/j.msard.2022.103597

Osborne, B., & Balcer, L. J. (2023). Optic neuropathies. Section Ed: Brazis PW. Up to date.

Palmer, B. A., Gur, D., Weiner, S., Addadi, L., & Oron, D. (2018). The organic crystalline materials of vision: structure–function considerations from the nanometer to the millimeter scale. Advanced Materials, 30(41), 1800006. https://doi.org/10.1002/adma.201800006

Park, S. H., Park, C. Y., Shin, Y. J., Jeong, K. S., & Kim, N. H. (2020). Low contrast visual acuity might help to detect previous optic neuritis. Frontiers in Neurology, 11, 602193.

Rajkarnikar, S., Gurung, A., & Pant, S. N. (2021). The Clinical Profile of Idiopathic Optic Neuritis at the Ophthalmology OPD of Tertiary Centre of Army Hospital, Nepal. Medical Journal of Shree Birendra Hospital, 20(1), 70-76. https://doi.org/10.3126/mjsbh.v20i1.28789

Salmon, J. (2019). Kanski's Clinical Ophthalmology E-Book: A Systematic Approach. Elsevier Health Sciences.

Sánchez, M. I. S., Uribe, P. A. F., Moncada, J. P. G., Rodríguez, G. G. C., Acuña, D. A., Vega, R. C., ... & Barrios, N. P. (2023). Demyelinating and Autoimmune Optic Neuritis: Approach and Management. https://dx.doi.org/10.38125/OAJBS.000534

Sun, P., Li, Q., Li, H., Di, L., Su, X., Chen, J., & Chai, X. (2019). Depth-Resolved physiological response of retina to transcorneal electrical stimulation measured with optical coherence tomography. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 27(5), 905-915. https://doi.org/10.1109/TNSRE.2019.2912168

Wang, X., Zhu, Q., Yan, Z., Shi, Z., Xu, Y., Liu, Y., & Li, Y. (2023). Enlarged choroid plexus related to iron rim lesions and deep gray matter atrophy in relapsing-remitting multiple sclerosis. Multiple Sclerosis and Related Disorders, 104740. https://doi.org/10.1016/j.msard.2023.104740

Published

13-05-2023

How to Cite

Islam, S. B. ., Shah, M., Abbas, . S. ., Ullah, S., Khan, S. A., & Ullah, M. . (2023). Optic Neuritis: Evaluation of Visual Acuity and Contrast Sensitivity. A Hospital Based Cross Sectional Study. Malaysian Journal of Medical Research (MJMR), 7(2), 34-39. https://doi.org/10.31674/mjmr.2023.v07i02.005

Metrics