Reviewing the Annals of Selayang Neuro Emergency Stroke Thrombolysis Initiative

Fatin Suraini Mazn*, Gurjeet Singh a/l Harvendhar Singh

Emergency Medical Department, Hospital Selayang, Malaysia 68100 Rawang Selangor, Malaysia

Corresponding Author’s Email: fatinsuraini93@gmail.com


Introduction

Stroke is one of the leading cause of death in Malaysia (Tan, 2022). Hence, Hospital Selayang Emergency Department (ED) implemented a stroke protocol. This program will help to accelerate the process of thrombolysis (Madhok,2019). An organised flow and assessment is created to ensure the indications for thrombolysis is present and prevent complications (Singh, 2023).

Methodology

Patients that presented with stroke like symptoms from the 1st of February 2023 till 31st May 2023 is included in the article.

Patients that presented within the period of 4.5 hours are triage to resuscitation zone and attended immediately to rule out stroke mimics. Patients are then referred to medical department and to exclude any contraindication for thrombolysis and sent for computerised tomography (CT) brain scan. By reviewing the CT brain images and using the National Institutes of Health Stroke Scale (NIHSS) score, the severity of the stroke is determined and whether thrombolysis is needed.

Results

A total of 14 patients were included in this article. All patients were able to receive neuro- medical clerking within 15minutes as the medical department medical officer is readily positioned in resuscitation zone during office hours.

13 out of 14 patients were able to do CT brain within 25 minutes; however this could be improved if the CT room is available within ED itself.

Out of the 14 patients, only 2 patients were thrombolysed. The most common reason being the patient has low NIHSS score and exceeded the 4.5 hours window period for thrombolysis.

Conclusion

Only 14 patients with acute stroke presented duing this time which shows that the public’s stroke recognition can be improved as not many stroke cases were presented in time. Also, the immediate recognition by PHC team and sending to a stroke capable centre could improve the early recognition (Saini,2019).

93% of patients met the time to CT from the ED. A good stroke protocol with good interdepartmental collaboration between Emergency Department, Neuromedicine, Radio Department as well as good enforcement leads to good response timings and activation (DAS,2021).

Only 14% of patients were thrombolysed during this period. This could be due to the risk and benefit ratios of thrombolysis are scrutinized to prevent complications, recognition of stroke mimics, and enforcement of the NIHSS score prior to thrombolysis with ASPECT scoring as addition to help objectively determine the need for thrombolysis (Lee.2023).


References

Tan, K. S., & Venketasubramanian, N. (2022). Stroke burden in Malaysia. Cerebrovascular Diseases Extra, 12(2), 58-62. https://doi.org/10.1159/000524271

Madhok, D. Y., Keenan, K. J., Cole, S. B., Martin, C., & Hemphill 3rd, J. C. (2019). Prehospital and emergency department-focused mission protocol improves thrombolysis metrics for suspected acute stroke patients. Journal of Stroke and Cerebrovascular Diseases, 28(12), 104423. https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.104423

Singh, G., bin Noorul Ameen, M. N. A., & Darshan, S. (2023). Recognizing Pearls and Pitfalls in The Emergency Medicine Department During Initiation of a New Stroke Thrombolysis Service. Malaysian Journal of Medical Research (MJMR), 7(1), 7-10. https://doi.org/10.31674/mjmr.2023.v07i01.002

Saini, V., Guada, L. and Yavagal, D.R., 2021. Global epidemiology of stroke and access to acute ischemic stroke interventions. Neurology, 97(20 Supplement 2), pp.S6-S16.

DAS, M. (2021). PROJECT REPORT ON “AN OVERVIEW OF RENAISSANCE HOSPITAL AND ITS (Doctoral dissertation, CITY COLLEGE).

Lee, K. S., Siow, I., Zhang, J. J., Syn, N. L., Gillespie, C. S., Yuen, L. Z., ... & Yeo, L. L. (2023). Bridging thrombolysis improves survival rates at 90 days compared with direct mechanical thrombectomy alone in acute ischemic stroke due to basilar artery occlusion: a systematic review and meta-analysis of 1096 patients. Journal of NeuroInterventional Surgery, 15(10), 1039-1045. http://dx.doi.org/10.1136/jnis-2022-019510